Azopharma offers custom synthesis in support of pharmaceutical product development from milligram to kilogram quantities.
Services/Capabilities:
- cGMP production of New Chemical Entities
- Reference standards
- Impurity standards
- Analytical marker compounds
- Metabolites
- Isotopic labeling
- Medicinal chemistry libraries
- Novel route design
- Literature synthesis
- Cold and hot labeled synthesis
- Process design and scale-up
- DMF support
Our Ph.D. synthetic organic chemists have extensive experience in many different building block reactions including:
- Acetylation
- Acylation
- Alkylation
- Amidation
- Amination
- Benzoylation
- Bromination
- Carbamoylation
- Carbonylation
- Claisen Condensation
- Cyclization
- Dealkylation
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- Decarboxylation
- Dehydrogenation
- Diels-Alder
- Distillation
- Esterification
- Friedel-Crafts
- Grignard
- Hydrogenation
- Hydrolysis
- Imidization
- Methylation
- Mannich
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- Neutralization
- Nitration
- Oxidation
- Quaternization
- Reduction
- Ring Closure
- Sandmeyer
- Saponification
- Strecker
- Sulfonation
- Transesterification
- Wittig
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Azopharma has expertise working with a variety of compound classes including:
- Morphine derivatives
- Taxol analogs
- Tricyclic antidepressants
- Guaifenesin derivatives
- Lactone rings
- Analgesics
- Peptide linkages and conjugates
- Thiol molecules