Small-Scale Synthesis

Azopharma's staff performs small-scale custom synthesis for discovery, preclinical and clinical material needs.

Our team has experience synthesizing various chemical compounds including:

Pharmaceutical APIs
Steroids, opiates, nucleotides, indoles, quinones, anthraquinones and nitroxides
Unnatural amino acids, thiols and phosphines
Contrast agents and macrocylic host-guest compounds
Heterocycles (N,O,S), organophosphorous and organosilicon compounds
Polymers

We also have experience with the following chemistries:

Oxidation (C102, Swern, periodate, Cr, oxygen and ozone,
Dess-Martin, peroxides, Hg)
Carbanion (Li, Mg, Mn) and Organometallic (Sn, Ge, Pd, Cu, Pt, Ru, Rh, Os)
Reduction (hydride, dissolving metal), Hydrogenation/Hydrogenolysis
(Pd, Pt, Rosenmund, RaNi)
Halogenation (SOX2, X2, NXS, PX3) and Dehydrohalogenation
Condensation, Hydrolysis, Amination and Esterification